Can Statin Therapy Cause Diabetes Mellitus?
- Statin therapy has a well-established role in the treatment of high cholesterol and reduction of cardiovascular disease risk.
- Generally, statin therapy is considered safe and has a side effect profile with a low incidence rate that is also reversible.
- Statin therapy in patients with increased cholesterol or existing cardiovascular disease has been reported to potentially contribute to diabetes mellitus (DM).
- Statin medications may cause an increase in blood sugar that can potentially lead to DM or similar signs and symptoms of DM.
- For secondary prevention of cardiovascular events, statin therapy has been established. However, when it comes to secondary prevention the risk-benefit of statin therapy is less clear.
There is a relatively decent amount of data that assesses the effects of statin therapy on the induction of type 2 diabetes mellitus (T2DM). In a retrospective cohort study, 265,414 patients aged 40-70 years of age were evaluated for statin-induced DM. In this study group, 17.9% of the patient were treated with statins. In the four years this study was conducted, there were 5,157 new cases of cardiovascular disease and 11,637 new DM diagnoses. The results showed that low-intensity statin therapy in which the patient was over 50% adherent was associated with an increased risk of DM in those with low or intermediate baseline CV risk. In patients with high CV risk, the same was not true and there was no association. In patients that started statin therapy with low CV risk, no CV protective benefit was observed. The researchers calculated the number needed to harm (NNH) for one patient treated with a low-intensity statin that was above 50% adherent as 40. In those with intermediate and high CV risk, the NNH was 50 and 200, respectively. This study concluded that low-dose statin therapy in those with high CV risk is beneficial, however may be detrimental to those with low CV risk.
A meta-analysis was performed to investigate the association of statins and DM further . The analysis identified studies in the Embase, Cochrane, and PubMed databases. In total there were 29 trials included in the analysis that consisted of 163,039 subjects. The analysis found that statin medications significantly increased the likelihood of patients developing DM by 12%. Based on the results of the study, it also seems as though higher intensity statin medications such as atorvastatin and rosuvastatin have higher associated risks of leading to DM than do low-intensity statins. Looking further into the drug information data according to Lexicomp, atorvastatin’s adverse events include endocrine & metabolic disorders such as DM. It is stated that the risk of this adverse event is up to 6% .
- Porath A, Arbelle JE, Fund N, Cohen A, Mosseri M. Statin Therapy: Diabetes Mellitus Risk and Cardiovascular Benefit in Primary Prevention. Isr Med Assoc J. 2018;20(8):480-485.
- Thakker D, Nair S, Pagada A, Jamdade V, Malik A. Statin use and the risk of developing diabetes: a network meta-analysis. Pharmacoepidemiol Drug Saf. 2016;25(10):1131-1149. doi:10.1002/pds.4020
- Atorvastatin Drug Information. In: Post TW, ed. UpToDate. Waltham, MA: UpToDate Inc.
How To Find The Right Cognitive Behaviour Therapist For You?
Cognitive behaviour therapy, sometimes known as CBT, is a type of psychological therapy that is beneficial in the treatment of a wide variety of mental health illnesses, such as anxiety disorders, depression, and addiction. The primary goal of cognitive behavioral therapy (CBT) is to alter destructive patterns of thought and behavior by recognizing and disputing cognitive misconceptions.
If you are considering getting cognitive behavioral therapy (CBT), selecting the correct therapist to work with might be an important step on the path to better mental health. The following are some suggestions that can assist you in locating an appropriate cognitive behaviour therapist for your needs.
The first thing you should do while looking for a cbt thailand therapist is to speak with someone you have confidence in, such as your primary care physician, close friends, or members of your family. They might have had firsthand experience with cognitive behavioral therapy (CBT), or they might know someone who has. You may also contact your health insurance provider to obtain a list of CBT therapists that participate in their network.
Carry Out Some Study
When you have a list of potential therapists to choose from, the next step is to do some research to learn more about their credentials, years of experience, and approach to therapy. On the websites of professional organizations such as the American Psychological Association or the Canadian Psychological Association, you will be able to check their qualifications. You can learn about the experiences of other patients by reading internet reviews written by those individuals.
Verify Any Claims Of Specialization
Not many mental health professionals are certified to provide cognitive behavioral therapy (CBT), as it is a specialized form of talk therapy. You should look for therapists who have both specialized training in cognitive behavioral therapy (CBT) and expertise in treating the particular mental health illness that you are seeking help with. Because of this, the treatment that you receive will be as beneficial as is humanly possible.
Take Into Account The Logistics
When looking for a cognitive behavioral therapy (CBT) therapist, logistics should also be a major concern. Consider things like the location of the mental health retreat, where the therapist operates, whether or not they are available, and how much they charge. Choose a therapist whose office is easily accessible from where you live and whose hours are flexible enough to accommodate yours. Think about how much money you can set aside for therapy, as well as whether or not your health insurance would cover it.
Talk Things Out With The Therapist
It is crucial to visit with a potential therapist to discuss your concerns and treatment goals before making a commitment to therapy with a specific professional. This will provide you with insight into their method of treatment and allow you to determine whether or not they are a good fit for you. Ask them about their expertise and training in cognitive behavioral therapy (CBT), as well as their success rate in treating your specific illness, and their approach to therapy while you are meeting with them.
Trust Your Gut
When choosing a cognitive behavioral therapy (CBT) specialist, the degree to which you feel at ease in their presence is ultimately the most significant consideration. Put your faith in your gut feelings and select a therapist who you believe will pay attention to you, honor the things that are important to you, and recognize your worries. Keep in mind that therapy is a process in which participants work together and that for you to make progress, you need to feel that you are being protected and supported.
Finding the proper cognitive behaviour therapy is a vital step in achieving greater mental health, which is why you should take the time to do your research. You can select a therapist who is well-equipped to assist you in overcoming your mental health difficulties if you do your research, verify that they have a specialty, take into consideration the logistics, visit with the therapist, and trust your instinct.
6 Things To Do After Being Involved in a Rideshare Accident
Rideshare programs have become a popular choice for traveling. Most people without cars use them to get around. That said, rideshare accidents have also become common, and some lead to severe injuries. Because these drivers work for rideshare companies, most people often wonder about the steps to take after getting involved in an accident with such drivers. Here are some of the things you need to do.
Check for Injuries
The first thing you need to do after an accident is to check for injuries. Your health should be your concern. If you have other passengers in the car and you can move, check if they are injured as well. Don’t move anyone who is unconscious, as you don’t know the extent of their injuries. If you have first aid knowledge, you can help, but don’t give medical care beyond what you’re qualified to do. You may end up causing more injuries.
Seek Medical Care
Seek medical attention even if you can’t see any injuries. Accidents tend to shock the people involved, which can prevent them from feeling any pain at the moment. The doctor will evaluate you and give you a clean bill of health if you’re fine or treat you for any injuries. The effects of car accidents can be long-lasting, especially if you ignore immediate medical care. That’s why it’s advisable to ensure you are okay.
Document the Scene of an Accident
If you can move, document the accident scene by taking photos and videos. Capture the location of each vehicle, the damage caused, nearby traffic signs and lights, and the surroundings. Even if you’re a passenger who ordered the rideshare vehicle, you should still collect evidence. It will come in handy when filing an injury claim. Plus, the evidence can prove who is responsible for the accident.
Report the Accident to the Police
Always call the police after being hit by a car. Often, most people try to solve the issue independently, only for the arrangement to backfire. Let the police come and write a report of the accident. You’ll need it when filing an insurance claim. The police will speak to everyone at the scene and write a neutral record. They might also issue a ticket to the driver who violated traffic laws.
Contact An Attorney
Most people assume you should only contact a lawyer when the insurance company is frustrated. However, you need to involve them from the start. Find a good car accident lawyer at Reinartz Law Firm who will advise you about the steps to take. Rideshare companies and insurance carriers have a lot of experience with car accident claims and can try to lowball you. A lawyer will argue on your behalf and ensure you get fair compensation.
Contact Your Insurance Company
Always contact your insurance company, regardless of who will be found at fault after a rideshare accident. That simple call will get the ball rolling on your compensation. It’s also an official notice, just in case things don’t go as planned and you have to depend on your policy to cover the expenses you incur. While the rideshare driver’s insurance coverage may pay for your expenses, their coverage may not be adequate. In such a case, your underinsured coverage will cover the extra cost, saving you additional expenses.
Getting hit by a rideshare driver is complicated. That’s because the drivers have to get their personal insurance coverage, and the rideshare company only provides additional coverage. As such, it can be hard to know who to deal with. That’s why you need an experienced car accident lawyer who will know how to navigate all these and secure you a fair settlement.
Fruits for Fitness: Top Ten Health Benefits of Fruits
Fruits are not only delicious but they are also packed with essential nutrients that can help to improve overall health and well-being. From reducing the risk of chronic diseases to improving digestive health and boosting immune function, there are many benefits to consuming a variety of fruits as part of a balanced diet.
In this article, we will explore the numerous health benefits of fruits and provide examples of fruits that are particularly beneficial for each benefit. So, read on to learn more about the amazing health benefits of fruits and how you can incorporate them into your diet for optimal health.
Fruits are an essential component of a healthy diet and provide a variety of health benefits. Some of the health benefits of fruits include:
1. Fruits are Nutrient Rich
Fruits are rich in vitamins, minerals, and other nutrients that are essential for the proper functioning of the body. Many fruits are rich in a variety of nutrients, but some particularly nutrient-dense fruits include berries (such as blueberries, raspberries, and strawberries), citrus fruits (such as oranges and grapefruits), kiwifruit, mangoes, and papayas.
2. Low in Calories
Most fruits are low in calories and high in fiber, which can help to reduce the risk of obesity and other chronic diseases. Fruits that are particularly low in calories include watermelon, cantaloupe, honeydew melon, strawberries, raspberries, blackberries, and blueberries.
3. Rich in Antioxidants
Fruits are rich in antioxidants, which can help to prevent damage to the cells in the body and reduce the risk of chronic diseases such as cancer, heart disease, and Alzheimer’s disease. Berries (such as blueberries, raspberries, and strawberries), pomegranates, grapes, and cherries are particularly rich in antioxidants.
4. Reduce the Risk of Chronic Diseases
The consumption of fruits has been linked to a reduced risk of chronic diseases such as heart disease, stroke, diabetes, and some cancers. Apples, oranges, bananas, berries, grapes, and kiwifruit have all been linked to a reduced risk of chronic diseases.
5. Improve Digestive Health
The fiber in fruits can help to promote healthy digestion and reduce the risk of constipation. Fruits that are particularly high in fiber and can help promote healthy digestion include raspberries, blackberries, pears, apples, bananas, and oranges.
6. Skin Health and Appearance
Fruits are rich in vitamins and antioxidants, which can help to improve the health and appearance of the skin. Fruits that are particularly rich in vitamin C and other antioxidants, which can help to improve the health and appearance of the skin, include kiwifruit, oranges, papayas, strawberries, and watermelon.
7. Increases Immunity
Fruits are rich in vitamin C, which can help to improve immune function and reduce the risk of infections. Fruits that are particularly high in vitamin C and can help to improve immune function include kiwifruit, oranges, grapefruit, strawberries, and papayas.
8. Lower the Risk of Stroke
Some studies have found that consuming fruits, especially berries and citrus fruits, may help to lower the risk of stroke. This may be due to the anti-inflammatory and antioxidant compounds found in fruits. Some fruits that may be especially beneficial for reducing the risk of stroke include citrus fruits (such as oranges and grapefruit), berries (such as strawberries, blueberries, and raspberries), and apples.
9. Improve Mental Health
Fruits, especially berries and citrus fruits have been linked to improved cognitive function and a reduced risk of cognitive decline. This may be due to their high content of flavonoids and other antioxidants. Berries (such as blueberries and strawberries) and citrus fruits (such as oranges and grapefruit) are particularly rich in flavonoids and other antioxidants that have been linked to improved cognitive function.
10. Reduce Inflammation
Fruits, especially those that are rich in antioxidants, have anti-inflammatory properties that can help to reduce inflammation in the body. This may help to reduce the risk of chronic diseases such as heart disease, diabetes, and cancer. Fruits that are particularly high in antioxidants, such as berries (such as blueberries, raspberries, and blackberries), cherries, and pomegranates, have anti-inflammatory properties that can help to reduce inflammation in the body.
6 Dance Styles That Can Boost Your Fitness
“Dance is the hidden language of the soul”- Martha Graham.
It is one of those activities which can liberate you from stress and elevate your mood. And you must be very much aware of the fact that dancing on a regular basis is one of the best ways to remain fit, both mentally and physically. Why is it different and better than the conventional style of working out? Because it is total fun, you don’t even realize that you are working out every muscle of yours.
Check out these 5 popular dance styles which will make your fitness journey a lot easier and more fun!
The dance genre was developed in the mid-twentieth century as one of the most expressive dance styles. The popularity of the genre has sky-rocketed around the globe, especially in Europe and America. It has elements of lyrical and classical ballet and jazz dance forms.
When you will acquire the skill of the dance form you will realize that it empowers you to express your deepest feelings through your body movements. One can choose a wide array of music to deploy the techniques of a contemporary dance performance.
2. Dance Yoga
Yoga is undoubtedly one of the most practiced posture-based mental, spiritual, and physical fitness techniques. With increasing popularity, yoga enthusiasts have devised a dance style that is widely grabbing a lot of attention among fitness enthusiasts. If you believe in the power of Yoga, you should definitely try Dance Yoga which incorporates moves inspired by Yoga asanas. These moves can be very basic combined with simple music like chants or drum beats or they can be complicated asanas combined with fast-beat music.
This workout style is a perfect way to reap the benefits of yoga along with the joy that comes along with its music. If dance is not your style, you can simply register yourself in online yoga classes.
3. Hip Hop
This dance form has been representing the young generation for three decades. The more you understand and practice Hip-Hop, you’ll realize that it is a culture more than a dance form. It is made up of exciting elements of music and arts like B-boying, Graffiti, MCing, and Deejaying. And even if you have developed a little skill in the dance style, you will understand that it is all about attitude, self-knowledge, and expression.
If you are a fitness freak, you’ll soon discover hip-hop hits in your workout playlist. The fast-paced music, the beats, and the lyrics literally multiply the zeal and the effort you put into your fitness sessions.
The Latin dance style, Zumba is widely practiced as a group workout, around the globe. The interval training dance style incorporates low and high-intensity dance moves, designed to enhance heart health. To groove on the fusion of Latin and international music will give you a party-like experience. And you won’t even realize that you are working on those extra pounds.
Whether you are dancing alone at home or grooving with a group in a Zumba class, you will enjoy the dance numbers and the moves, even if you are not that good at it. In a good 60-minute Zumba session, you can burn an average of 370 calories, which is more than the calories burnt in aerobics and kickboxing. With consistency, you can achieve great flexibility, strong core muscles, and a great physique.
5. Masala Bhangra
Masala Bhangra Workout has revolutionized the high-energy Indian folk dance of Bhangra. It is a perfect alchemy of Bhangra, Bollywood dance style, Hip-Hop, and Salsa. It is fun to incorporate this dance style as a workout regimen as it is fun and rigorous at the same time. A good Masala Bhangra workout training can help you burn approximately 500 calories, which is more than burnt in Zumba!
The high-intensity workout form, Masala Bhangra is a great way to work on your stamina, balance, endurance, and overall body strength. You can view some of the cool moves on youtube to ensure that it is one of the most recent and interesting ways to boost your fitness.
6. Belly Dancing
This core-strengthening dance form is a great workout option. Although it goes way back to the 18th century, it is incorporated in so many movies and global stages today. Besides its popularity, it has several benefits to offer. It especially targets the stomach, oblique, glutes, and thighs. Moreover, it helps in enhancing posture, body coordination, and balance.
The music is also rich in beats and rhythm. If you are impressed with this dance form you can explore some awesome belly dance classes architected by highly trained and acclaimed teachers on ipassio. Once you will add this dance form to your workout regimen, you will realize that it is inexplicably addictive.
Dance your way to Fitness
“To dance is to be out of yourself, larger, more beautiful, more powerful. This power, it is glory on earth and it is yours for the taking”- Agnes De Mille
So why not equip yourself with the powers of a dance style of your choice? Because, if a person is fit and happy from within, it reflects physically. You will feel younger, stronger, and more confident if you are consistent with your dance practice.
So give a fun angle to your workout sessions with passion dance classes from the convenience of your homes.
Things To Know About Tests and Procedures Used to Diagnose Cancer
Cancer diagnoses are a terrifying reality for many people, and the tests and procedures used to confirm them can be confusing and overwhelming. Understanding the different types of tests and methods used to diagnose cancer is essential for anyone who wants to make an informed decision about their care.
This blog post will discuss some critical things about tests and procedures used to diagnose cancer, including what they are, why they’re done, how they’re performed, and what results they can provide.
We’ll also discuss common treatments that may be recommended after a diagnosis. Many CROs manage clinical trials for various diseases, and some CROs specialize in oncology trials. Knowing more about how cancer is diagnosed can help you make decisions that will be vital in your fight against the disease.
Imaging Tests for Cancer
Depending on the type of cancer, your doctor may order one or more imaging tests to help make a diagnosis. Imaging tests use x-rays, magnetic fields, sound waves, or radioactive substances to create pictures of the inside of your body. Some imaging tests are used to look for cancer, while others are used to find out how far it has spread.
Your doctor may order a computed tomography (CT) scan to look for cancer in your body. During a CT scan, you lie on a table, and an x-ray machine rotates around you, taking detailed pictures of your organs and structures. A CT scan can sometimes find cancers too small to be seen with other imaging tests.
Your doctor may also order a magnetic resonance imaging (MRI) scan to look for cancer in your body. An MRI uses powerful magnets and radio waves to create detailed pictures of your organs and structures. MRI scans can sometimes find cancers too small to be seen with other imaging tests.
Your doctor may also order an ultrasound exam to look for cancer in your body. During an ultrasound exam, a transducer device is placed against your skin. The transducer emits sound waves that bounce off tissues and organs inside your body and create echoes. These echoes are converted into images that can be seen on a monitor. Ultrasound exams can sometimes find cancers too small to be seen with other imaging tests.
Several types of biopsy procedures can be used to diagnose cancer. The type of biopsy procedure used will depend on the location and type of cancer being diagnosed.
- A needle biopsy is a common type of biopsy procedure. A needle biopsy can be performed using a fine or core needle. A fine needle biopsy uses a thin needle to remove cells from the body. A core needle biopsy uses a giant hand to remove a small piece of tissue from the body.
- A surgical biopsy is another type of biopsy procedure. A surgical biopsy involves removing all or part of the tumor for examination. This type of Biopsy is usually done under general anesthesia, which means you will be asleep during the procedure.
- A skin biopsy is another procedure that can be used to diagnose skin cancer. A skin biopsy involves removing a small sample of skin for examination. This type of Biopsy can be done using a razor blade, punch Biopsy, or excisional Biopsy.
Endoscopic procedures are a group of diagnostic tests and procedures using a long, thin tube with a light and camera attached. The tube is inserted through a small incision in the body or natural openings, such as the mouth. Endoscopic procedures allow your doctor to see inside your body without making a large incision.
There are many different types of endoscopic procedures, each with its own set of risks and benefits. Your doctor will discuss each procedure’s risks and benefits before deciding which is right for you.
Some standard endoscopic procedures used to diagnose cancer include:
A colonoscopy examines the large intestine (colon) lining for abnormalities. A colonoscopy can also remove polyps, which are growths on the colon lining that may become cancerous if left untreated.
Gastroscopy examines the stomach’s lining for abnormalities. A gastroscopy can also be used to remove polyps from the stomach lining.
A bronchoscopy is used to examine the airways for abnormalities. A bronchoscopy can also take biopsies (tissue samples) from suspicious areas.
For abnormalities, an endoscopic ultrasound examines the digestive organs (such as the stomach, small intestine, and colon). Endoscopic ultrasound can also be used to take biopsies from these organs.
A cystoscopy examines the bladder and urethra (the tube leading from the bladder to the outside of the body) for abnormalities. A cystoscopy can also be used to take biopsies from suspicious areas of the bladder or urethra.
Endoscopic procedures are usually performed on an outpatient basis, meaning you will not have to stay in a hospital overnight. The procedure may cause slight discomfort but should not cause severe pain. Your doctor will provide detailed instructions on preparing for your procedure and what you should expect during and after it.
Many different types of surgical procedures can be used to diagnose cancer. The most common type of surgery is a biopsy, in which a small tissue sample is removed from the body for examination. Other surgeries used to diagnose cancer may include fine needle aspiration, core needle biopsy, and incisional Biopsy. Surgery is usually only performed if there is a suspicion of cancer-based on other tests, such as X-rays or CT scans.
In some cases, surgery may also be used to treat cancer. This type of surgery is often called an excisional biopsy or resection. The entire tumor or affected tissue area is removed from the body during this procedure. Surgery can also remove lymph nodes that may contain cancerous cells.
Molecular diagnostics is a rapidly evolving field that offers new hope for more accurate, earlier, and less invasive cancer detection. Molecular tests are performed on a patient’s DNA to look for specific cancer-related changes (mutations). These tests can be used to detect the presence of cancer, to help diagnose the type and stage of cancer, and to guide treatment decisions.
Molecular diagnostics is still a relatively new field, and there is much ongoing research to improve its accuracy and broaden its applications. However, molecular tests are already used in clinical practice to inform cancer diagnosis and treatment decisions. For example, the genetic test known as fluorescence in situ hybridization (FISH) can detect certain chromosomal changes associated with specific types of cancer. FISH testing is often used along with other diagnostic tests, such as cytogenetic testing, for a more definitive diagnosis.
Molecular diagnostics holds excellent potential for improving cancer diagnosis and treatment. As this field continues to evolve and new technologies become available, researchers hope that molecular diagnostics will become an even more valuable tool in the fight against cancer.
A cancer diagnosis can be a complicated process, and many tests and procedures are used for diagnosis. We hope this article has provided you with an overview of the standard tests used to diagnose cancer so that you can feel more informed about the steps involved. It is essential to consult your doctor if you have any questions or concerns about the test results, as they can provide advice tailored specifically to your situation.
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