Modafinil vs. Adrafinil

Modafinil vs. Adrafinil: Here’s Why You Should Avoid Adrafinil

Are you constantly struggling to stay awake during the day? Are you a night owl who has trouble falling asleep at a decent hour?

Smart drugs may be just the right solution for you.

Modafinil and Adrafinil both are popular nootropics that people use to enhance cognitive skills like focus and memory retention.

Both are smart drugs but we would suggest you avoid Adrafinil and stick to more popular variants of generic modafinil instead.


Find more details in the post.

Table Of Content

  1. Modafinil vs Adrafinil
  2. Modafinil
    • Modafinil Uses
    • Modafinil Side Effects
  3. Adrafinil
    • Adrafinil Uses
    • Adrafinil Side Effects
  4. Why You Should Avoid Adrafinil?
  5. Bottomline

Modafinil vs Adrafinil

Modafinil and Adrafinil are medications used to treat excessive sleepiness caused by narcolepsy, shift work sleep disorder, and obstructive sleep apnea. It promotes wakefulness by stimulating certain areas in the brain.

But Modafinil and Adrafinil aren’t just for those with medical sleep disorders.

Their off-label use as a cognitive enhancer has become increasingly popular, especially among high achievers in competitive industries such as finance, technology, and academia.

However, there is a significant difference between these two nootropics as they both work quite differently.

Modafinil and Adrafinil can improve focus, concentration, and alertness – making it appealing for those who want an extra boost to get through their busy days, get better grades, or ace those daunting meetings and tasks.

Are you looking to boost your brain power and enhance your cognitive skills?

Look no further, because we’ve got the scoop on which smart drug between Modafinil and Adrafinil is best for you.


First up, let’s talk about Modafinil.

Often prescribed for ADHD, this medication can also increase focus and attention in individuals even without the disorder. The smart drug can do wonders when used to enhance cognitive skills.

Pilots, politicians, students, CEOs, gamers, and many more stay on top of their game in life with the help of modafinil.

Have you ever felt like you just couldn’t stay awake during that early morning meeting or cram session?

Modafinil could just be the ultimate right thing for you!

Modafinil has to be the most popular nootropic available at the current date and there are tons of ways you can purchase the prescription medicine.

Modafinil Uses

  • Improved focus and concentration: Modafinil has been shown to enhance cognitive function, allowing users to stay on task for longer periods.
  • Enhanced motivation: Modafinil has been shown to increase dopamine levels, leading to increased drive and enthusiasm for tasks.
  • Improved short-term memory: In addition to improving focus, Modafinil has also been shown to improve the ability to remember and recall information.
  • Increased problem-solving skills: Modafinil has been shown to improve complex decision-making and enhance creativity.
  • Enhanced mood: Modafinil has been shown to have a positive impact on mood, reducing fatigue and improving overall feelings of well-being.

Modafinil Side Effects

Like any other prescription medication, Modafinil does come with potential risks and side effects. It’s important to consult a doctor before taking Modafinil, especially if you have a history of mental health issues or heart problems.

Here are some possible side effects of using modafinil which is not common and usually disappear in a few days:

  • Dehydration
  • Skin rashes
  • Nausea
  • Headache
  • Stomach Issues

But before you freak out and swear off Modafinil, it’s important to remember that these side effects are not common and happen in only a small percentage of users. As with any drug, it’s important to weigh the potential benefits before deciding.


Adrafinil is a smart drug, also known as a nootropic, that is used to increase alertness and productivity.

It was originally developed in the 1970s for people with narcolepsy but has since become popular among students and professionals looking for an extra cognitive boost.

Adrafinil works by increasing the release of certain neurotransmitters in the brain, specifically dopamine and norepinephrine.

But, that’s not all.

Adrafinil is a prodrug that converts into modafinil inside your stomach after reacting to an enzyme.

Simply put, Adrafinil is a medication that is inactive when you take it and gets activated inside your liver by turning into modafinil.

However, in this process, the efficacy and time to show effects become lesser and delayed.

Adrafinil Uses

Adrafinil works similarly to modafinil as it is a precursor to the latter smart drug. The benefits of using adrafinil are similar to modafinil.

  • Adrafinil can improve alertness and attention, allowing you to power through those pesky all-nighters or intense workdays.
  • It can also enhance cognitive function, helping to improve memory and problem-solving skills.
  • Adrafinil has been shown to have neuroprotective properties, potentially slowing down the effects of aging on the brain.

Adrafinil Side Effects

Adrafinil needs to be converted in the liver into Modafinil before it can actually have any effects on the brain. This means that Adrafinil puts extra strain on the liver, potentially leading to liver damage.

Adrafinil is a prodrug. Pro drugs are often designed to maximize the active ingredient potency by delaying the effects until it reaches desired site of action.

Adrafinil being a pro-drug becomes less effective than more potent modafinil and has a shorter half-life.

But seriously, prodrugs are otherwise useful because they can target specific areas of the body and have less severe side effects.

Why You Should Avoid Adrafinil?

You will need to take more adrafinil to get the same effects with the same amount of modafinil.

The mechanism of action is different.

Here’s where things get a little funky, adrafinil is a precursor to another popular smart drug, Modafinil.

So, adrafinil gets converted into Modafinil in the liver, so technically speaking, taking adrafinil is just a roundabout way of taking Modafinil.

Plus, the amount of modafinil left after the conversion is way less than what you pop in.

So why would anyone bother hurting their liver with adrafinil instead of just taking Modafinil directly?


Modafinil is a go-to choice for students cramming for exams or professionals trying to up their game at work.

But don’t just take our word for it, 2017 study found that modafinil improved performance on a range of cognitive tasks, including memory, planning, and decision-making.

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Christophe Rude

Christophe Rude

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